PUBLICATION

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Liraglutide in Children and Adolescents with Type 2 Diabetes

Author: William V. Tamborlane, M.D., Margarita Barrientos-Pérez, M.M.S.C.I., Udi Fainberg, M.D., Helle Frimer-Larsen, M.Sc., Mona Hafez, M.D., Paula M. Hale, M.D., Muhammad Y. Jalaludin, M.D., Margarita Kovarenko, M.D., Ingrid Libman, M.D., Jane L. Lynch, M.D., Paturi Rao, Ph.D., Naim Shehadeh, M.D., Serap Turan, M.D., Daniel Weghuber, M.D., and Timothy Barrett, Ph.D. for the Ellipse Trial Investigators*
Date of publication: 28/04/2019

Metformin is the regulatory-approved treatment of choice for most youth with type 2 diabetes early in the disease. However, early loss of glycemic control has been observed with metformin monotherapy. Whether liraglutide added to metformin (with or without basal insulin treatment) is safe and effective in youth with type 2 diabetes is unknown.

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Glycemic effects of simvastatin: Where do we stand?

Author: Nor Razida Razali , Hasniza Zaman Huri, Luqman Ibrahim , Shireene Ratna Vethakkan , Bashar Mudhaffar Abdullah
Date of publication: 07/06/2018

In clinical practice, simvastatin is usually used in the treatment of dyslipidemia patients and those at risk of or with established cardiovascular disease. However, previous studies have shown that simvastatin has the potential to affect glycemic parameters as it reportedly reduced insulin secretion and sensitivity. The exact mechanism by which simvastatin affects glycemia is still unknown, but previous studies have postulated the involvement of the glucose-insulin secretion mechanism. This review focuses on the effects of simvastatin, either alone or in combination with other lipid lowering agents, antidiabetics and antihypertensives, on glucose homeostasis. Some studies have reported that simvastatin might impair the levels of glucose metabolism markers in the blood while others have reported no effect or improvement in glycemia.

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Altered circulating concentrations of active glucagon-like peptide (GLP-1) and dipeptidyl peptidase 4 (DPP4) in obese subjects and their association with insulin resistance

Author: Radwan H.Ahmed,Hasniza Zaman Huri, Sekaran Muniandy, Zaid Al-Hamodi, Boshra Al-absi, Abdulsamad Alsalahi, Muhammad FM Razif
Date of publication: 10/09/2017

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P 019 - Alterations of cultured myotubes and fasting plasma metabolite profiles related to mitochondrial dysfunction in Type 2 diabetes subjects

Author: Mohamad Hafizi AbuBakar,HasnizaZaman Huri,Nany Hairunisa
Date of publication: 06/07/2017

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Statin Therapy Prescribing for Patients with Type 2 Diabetes Mellitus: A Review of Current Evidence and Challenges

Author: Mohamed Hassan Elnaem,1 Mohamad Haniki Nik Mohamed,1 Hasniza Zaman Huri,2 Shah M. Azarisman,3 and Ramadan Mohamed Elkalmi4
Date of publication: 01/06/2017

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Apoptotic induction and inhibition of NF-κB signaling pathway in human prostatic cancer PC3 cells by natural compound 2,2'-oxybis (4-allyl-1-methoxybenzene), biseugenol B, from Litsea costalis: an in vitro study

Author: Abbaspour Babaei M, Zaman Huri H, Kamalidehghan B, Yeap SK, Ahmadipour F
Date of publication: 10/01/2017

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Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells

Author: Maryam Abbaspour Babaei,1 Behnam Kamalidehghan,2,3 Mohammad Saleem,4–6 Hasniza Zaman Huri,1,7 Fatemeh Ahmadipour1
Date of publication: 01/08/2016

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Clinical and genetic predictors of dipeptidyl peptidase-4 inhibitor treatment response in Type 2 diabetes mellitus

Author: Jazlina Liza Jamaluddin, Hasniza Zaman Huri & Shireene Ratna Vethakkan
Date of publication: 01/06/2016

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Genetic polymorphisms associated with overweight and obesity in uncontrolled Type 2 diabetes mellitus

Author: Nor Bahirah Kasim, Hasniza Zaman Huri, Shireene Ratna Vethakkan, Luqman Ibrahim & Bashar Mudhaffar Abdullah
Date of publication: 21/03/2016

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Genetic markers predicting sulphonylurea treatment outcomes in type 2 diabetes patients: current evidence and challenges for clinical implementation

Author: Hasniza Zaman Huri, N K Loganadan, , S R Vethakkan & Z Hussein
Date of publication: 26/01/2016

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